Infectious Disease Clinical Research Program

Infectious Disease Clinical Research Program

A Featured HJF Research Program

The Infectious Disease Clinical Research Program (IDCRP) was founded in 2005 under an interagency agreement between USU and the National Institute of Allergy and Infectious Diseases. The program conducts infectious disease clinical research that directly impacts military force readiness through a unique adaptive and collaborative network to advance clinical practice and health policy in the medical and scientific community.

From observational, longitudinal cohort studies of deployed and combat-injured service members to field-based interventional trials among recruits and the evaluation of the long-term outcomes of HIV infections, IDCRP conducts protocols that address critical gaps in the management and prevention of infectious diseases in the military.

The multi-site clinical research network established by IDCRP has supported a number of randomized clinical trials and observational studies in military populations:

  • Hyperimmune plasma for the treatment of severe influenza infection
  • Self-administration of intranasal influenza vaccine
  • Novel diagnostic tests to identify pathogens of traveler’s diarrhea
  • Treatment and prevention of traveler’s diarrhea
  • Safety and immunogenicity of a Staphylococcus aureus vaccine candidate
  • Hygiene-based prevention of skin and softtissue infection
  • HIV-associated neurocognitive disorders
  • Retrospective and prospective observational study of the natural history of HIV
  • Extent and transmission of ceftriaxoneresistant Neisseria gonorrhoeae.

Over the past decade, the military health research community continued to recognize and highlight IDCRP for its accomplishments across research areas, including acute respiratory infections, deployment- and travelrelated infections, HIV, sexually transmitted infections, and skin and soft-tissue infections.

In 2014, IDCRP presented as part of the Military Health System Research Symposium Media Roundtable, where David Tribble, M.D., DrPH, and Army Lieutenant Colonel Michael Ellis, M.D., served as experts on research related to fighting wound infections and antibiotic resistance.

Continuing its education and outreach mission, IDCRP hosted 33 student trainees from USU to conduct research across more than 20 active projects presented at the USU Research Days. Seven IDCRP trainees presented 10 posters at IDWeek 2014.

The year 2014 also saw the launch of the Executive Order for Combating Antibiotic-Resistant Bacteria. IDCRP is leading the way to identify and assess the public health impact of multidrug-resistant gonococci, as well as defining the epidemiology of Methicillinresistant Staphylococcus aureus skin and soft-tissue infections. Working with the DoD Multidrug-Resistance Surveillance Network at the Walter Reed Army Institute of Research and wound research programs at the Naval Medical Research Center, IDCRP has launched a retrospective study to evaluate the clinical outcomes and costs associated with acquisition of gram-negative multidrugresistant organisms from war trauma.