September 4, 2025
HJF supported the Uniformed Services University of the Health Sciences (USU) in completing the first year of a study titled Baseline and Longitudinal Assessment STudy of Explosive Ordnance Disposal (EOD) Males and Females for Alterations in Symptoms, Intellectual, and Sensory function (BLAST EMFASIS). The goal of the study is to investigate how subconcussive blast exposure affects brain function differently in male and female EOD technicians across all four military branches.
Led by Principal Investigator Michael Roy, M.D., MPH, Professor of Medicine, Director of the Division of Military Internal Medicine, and Deputy Director of the Military Traumatic Brain Injury Initiative at USU, the work builds on prior research that focused exclusively on males. The new prospective observational study, which includes both males and females, aims to fill critical gaps by assessing cognitive, sensory, and symptom changes following blast exposures. Advanced tools, like the Black Box Biometrics blast gauge system, and a battery of neurocognitive and physical assessments will collect valuable data. The study has enrolled 93 participants so far—46 women and 47 men—across 26 sites in 15 states, with plans to reach 100 total participants and follow them longitudinally or up to two years.
| Despite logistical challenges posed by the dispersed locations of EOD personnel as well as lower-than-expected rates of significant blast exposure due to strict safety practices, the research team has successfully conducted baseline and post-exposure assessments. Early findings will help clarify sex-based differences in brain impact from blast exposure that could potentially be influenced by neuroendocrine factors such as progesterone levels. | |
| The study also seeks to identify saliva biomarkers linked to blast effects and track symptoms related to PTSD, concussion, and insomnia. Presentations of preliminary data have been made at several scientific symposia, underscoring the importance of this work in addressing the high suicide rates and mental health risks faced by EOD technicians. |