Namrata Tiwari, PhD
My research focuses on translational pathophysiology at the intersection of trauma surgery, resuscitation science, neuroscience, and clinically relevant organ injury.
I investigate the molecular and cellular mechanisms underlying ischemia-reperfusion injury and multiorgan dysfunction following severe hemorrhage and cardiac arrest, using clinically relevant large-animal models to evaluate resuscitation strategies and identify biomarkers of tissue injury and recovery.
My work integrates serum biomarker analysis, multiplex immunoassays, histology and immunofluorescence, protein-expression studies, and mitochondrial and oxidative-stress assessments to connect mechanistic findings with clinically meaningful outcomes.
My broader research interests include neuroinflammation, sensory and neuroimmune signaling, organ cross-talk, and translating pathophysiologic mechanisms into diagnostic, prognostic, and therapeutic approaches for trauma, surgical, and critically ill patients.
Postdoctoral research training in translational trauma surgery, resuscitation science, ischemia-reperfusion injury, and multiorgan pathophysiology; doctoral training in neuroscience with emphasis on neuroinflammation, sensory biology, chronic pain, and peripheral and spinal mechanisms of organ cross-sensitization.
| Lackie M, Amberman K, Patterson K, et al. Aortic cardiopulmonary resuscitation in trauma: Extracorporeal CPR with controlled reoxygenation outperforms resuscitative thoracotomy in a porcine model of exsanguination arrest. Journal of Trauma and Acute Care Surgery. 2025. |
| Tiwari, N., Smith, C., Sharma, D., Shen, S., Mehta, P., & Qiao, L. Y. (2024). Plp1-expresssing perineuronal DRG cells facilitate colonic and somatic chronic mechanical pain involving Piezo2 upregulation in DRG neurons. Cell Reports, 43(5), 114230. https://doi.org/10.1016/j.celrep.2024.114230 Tiwari, N., & Qiao, L. Y. |
| Sex differences in visceral pain and comorbidities: Clinical outcomes, preclinical models, and cellular and molecular mechanisms. Cells, 13(10), 834; 2024 |
| Madar, J., Tiwari, N., Smith, C., Sharma, D., Shen, S., Elmahdi, A., & Qiao, L. Y. (2023). Piezo2 regulates colonic mechanical sensitivity in a sex specific manner in mice. Nature Communications, 14(1), 2158 |
Area of Research
Institution Affiliations
HJF Postdoctoral Fellow in support of the Department of Medicine, Uniformed Services University of the Health Sciences, Department of Surgery, Walter Reed National Military Medical Center.